RT Book, Section A1 Chuan, Alwin A1 Harrop-Griffiths, William A2 Hadzic, Admir SR Print(0) ID 1141730430 T1 The History of Local Anesthesia T2 Hadzic's Textbook of Regional Anesthesia and Acute Pain Management, 2e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071717595 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1141730430 RD 2024/04/19 AB The history of local anesthesia lacks a distinct Eureka moment. It can be argued that regional anesthesia does not have in its history a pivotal day that signified the wholesale change from an era before local anesthesia to the dawn of a new and wonderful age that included parts of the body being rendered insensate for therapeutic reasons. We do not have the equivalent of October 16, 1846, and the trembling hands of William Thomas Green Morton. What we have is a remarkably slow concatenation of the three elements necessary for the administration of the vast majority of local anesthetics: a syringe, a needle, and a local anesthetic drug. Many, however, would argue that to these three need be added several other factors: a detailed knowledge of anatomy and an appreciation of the body’s pain mechanisms and more objective methods to localize peripheral nerves and monitor administration of local anesthetics. We make no excuse for concentrating in this chapter on the early history of local anesthesia to dissect the development of these three vital components.