RT Book, Section A1 Colvin, Mai O. A1 Shiloh, Ariel L. A1 Eisen, Lewis A. A2 Oropello, John M. A2 Pastores, Stephen M. A2 Kvetan, Vladimir SR Print(0) ID 1136419877 T1 Lumbar Puncture T2 Critical Care YR 1 FD 1 PB McGraw-Hill Education PP New York, NY SN 9780071820813 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1136419877 RD 2024/04/16 AB KEY POINTSLumbar puncture (LP) is essential for the diagnosis of two treatable but potentially fatal conditions, central nervous system (CNS) infection and subarachnoid hemorrhage (SAH) with a negative computed tomography (CT) scan.LP can also be helpful in the differential diagnosis of other conditions including CNS malignancy, pseudotumor cerebri, and demyelinating diseases.Contraindications to LP include skin or soft tissue infection at the puncture site, acute spinal cord or head trauma, uncorrected severe coagulopathy, and brain shift secondary to a space-occupying lesion (SOL) or diffuse cerebral edema.Ultrasound-guided LPs reduce the risk of a failed or traumatic procedure, the number of needle insertions, and redirections compared to those performed without imaging.Complications from LP include brain herniation, headache, infection, spinal hematoma, and neurologic compromise.