RT Book, Section
A1 Bakker, Jan
A2 Oropello, John M.
A2 Pastores, Stephen M.
A2 Kvetan, Vladimir
SR Print(0)
ID 1136418403
T1 Controversies: ScvO2 Versus Lactate Clearance to Guide Resuscitation in Septic Shock?
T2 Critical Care
YR 1
FD 1
PB McGraw-Hill Education
PP New York, NY
SN 9780071820813
LK accessanesthesiology.mhmedical.com/content.aspx?aid=1136418403
RD 2024/04/20
AB Septic  shock  has  been  defined  as  a  state  in  which  hypotension  persists  despite  adequate  fluid  resuscitation  or  the  presence  of  a  lactate  level  more  than  4  mmol/L  (so-called  sepsis-induced  tissue  hypoperfusion)  in  patients  with  confirmed  or  suspected  infection.1  In  these  conditions,  the  Surviving  Sepsis  Campaign  Guidelines  suggest  to  restore  mean  arterial  pressure  (MAP)  more  than  65  mm  Hg  and  normalize  lactate  levels  and  central  or  mixed  venous  hemoglobin  saturation  (ScvO2/SvO2).1  Basically  this  reflects  restoring  perfusion  pressure,  improving  tissue  perfusion  and  restoring  the  balance  between  oxygen  delivery  and  oxygen  demand.