RT Book, Section
A1 Friedman, Oren A.
A2 Oropello, John M.
A2 Pastores, Stephen M.
A2 Kvetan, Vladimir
SR Print(0)
ID 1136412580
T1 Targeted Temperature Management After Cardiac Arrest
T2 Critical Care
YR 1
FD 1
PB McGraw-Hill Education
PP New York, NY
SN 9780071820813
LK accessanesthesiology.mhmedical.com/content.aspx?aid=1136412580
RD 2024/04/18
AB KEY  POINTSTargeted  temperature  management  (TTM)  refers  to  the  global  practice  of  controlling  temperature  after  cardiac  arrest.  Mild  therapeutic  hypothermia  refers  to  a  temperature  between  32°C  and  34°C.The  positive  effects  of  TTM  postarrest  are  believed  to  be  related  to  its  effects  in  suppressing  the  whole  body  reperfusion  injury,  and  preventing  exacerbation  of  that  injury  by  hyperthermia.Device  therapy  for  TTM  can  be  divided  into  surface  cooling  and  invasive  technology.The  three  phases  of  TTM  are  induction,  maintenance,  and  rewarming.There  is  no  consensus  on  the  optimal  rate  of  rewarming  although  it  is  recognized  that  uncontrolled  or  rapid  rewarming  can  lead  to  vasodilation,  hemodynamic  instability,  and  dangerous  electrolyte  shifts.The  lack  of  pupillary  reflexes  3  days  postcardiac  arrest,  the  presence  of  myoclonic  status  epilepticus  (MSE),  and  the  absence  of  somatosensory-evoked  potentials  (SSEPs)  all  very  likely  portend  an  extremely  poor  prognosis.