RT Book, Section A1 Friedman, Oren A. A2 Oropello, John M. A2 Pastores, Stephen M. A2 Kvetan, Vladimir SR Print(0) ID 1136412580 T1 Targeted Temperature Management After Cardiac Arrest T2 Critical Care YR 1 FD 1 PB McGraw-Hill Education PP New York, NY SN 9780071820813 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1136412580 RD 2024/10/04 AB KEY POINTSTargeted temperature management (TTM) refers to the global practice of controlling temperature after cardiac arrest. Mild therapeutic hypothermia refers to a temperature between 32°C and 34°C.The positive effects of TTM postarrest are believed to be related to its effects in suppressing the whole body reperfusion injury, and preventing exacerbation of that injury by hyperthermia.Device therapy for TTM can be divided into surface cooling and invasive technology.The three phases of TTM are induction, maintenance, and rewarming.There is no consensus on the optimal rate of rewarming although it is recognized that uncontrolled or rapid rewarming can lead to vasodilation, hemodynamic instability, and dangerous electrolyte shifts.The lack of pupillary reflexes 3 days postcardiac arrest, the presence of myoclonic status epilepticus (MSE), and the absence of somatosensory-evoked potentials (SSEPs) all very likely portend an extremely poor prognosis.