RT Book, Section A1 Webster, Lynn R. A2 Bajwa, Zahid H. A2 Wootton, R. Joshua A2 Warfield, Carol A. SR Print(0) ID 1131936848 T1 Novel Opioid Formulations T2 Principles and Practice of Pain Medicine, 3e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071766838 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1131936848 RD 2024/04/19 AB The medical profession recognizes the clinical value of prescribed opioids in treating noncancer pain that is persistent and recalcitrant to other therapies.1 However, the clinical benefit of conventional opioid formulations falls short of the need. Although analgesia from opioids is often limited to a subset of patients who achieve benefit, long-term analgesic efficacy is uncertain, and discontinuation of therapy due to adverse events or inadequate analgesia is common.2