RT Book, Section A1 Chai, Thomas A1 Hough, Stuart W. A1 Portenoy, Russell K. A1 Koyyalagunta, Dhanalakshmi A1 Driver, Larry C. A2 Bajwa, Zahid H. A2 Wootton, R. Joshua A2 Warfield, Carol A. SR Print(0) ID 1131935385 T1 Medical Management of Cancer Pain T2 Principles and Practice of Pain Medicine, 3e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071766838 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1131935385 RD 2024/03/28 AB Cancer pain is usually caused directly by neoplastic injury to pain-sensitive structures. For this reason, primary antineoplastic therapy, including radiation, chemotherapy, and palliative surgery, should be considered part of an analgesic strategy in some cases. When therapy directed at the tumor is inappropriate, is not feasible, is ineffective, or causes painful therapy-related syndromes, symptomatic analgesic therapies become the overriding concern. Opioid-based pharmacotherapy is the mainstay approach, but adjunctive anesthetic, surgical, psychiatric, and physical modalities may be essential as well (see Chapter 54, Cancer Pain Syndromes). Pharmacologic approaches may be systemic or regional (anesthetic).