RT Book, Section A1 Sang, Christine N. A1 Benavides, Rodrigo A2 Bajwa, Zahid H. A2 Wootton, R. Joshua A2 Warfield, Carol A. SR Print(0) ID 1131934406 T1 Central Neuropathic Pain Following Spinal Cord Injury T2 Principles and Practice of Pain Medicine, 3e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071766838 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1131934406 RD 2024/11/12 AB The development of debilitating central neuropathic pain (CNP), defined as pain caused by a lesion or dysfunction of the central nervous system (CNS),1,2 can occur after any lesion of the CNS, including demyelinating, vascular, infectious, inflammatory, and traumatic events. In contrast to CNP after stroke (including thalamic stroke resulting in Dejerine-Roussy syndrome), multiple sclerosis, and tumors,3,4 the prevalence of CNP after spinal cord injury (SCI) is high; most cite a prevalence ranging from 50% to 66%.5-8 With the number of individuals in the United States who have SCIs estimated to be as high as 1,275,000 and estimated lifetime costs from SCI ranging from $681,843 to more than $3 million if the injury is sustained at age 25 years,9 CNP after SCI has become a growing public health concern.