RT Book, Section A1 Minehart, Tiffany A1 Bellil, Lisa A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1135743192 T1 Pre-Eclampsia and Eclampsia T2 Anesthesiology Core Review: Part Two Advanced Exam YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259641770 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1135743192 RD 2024/04/20 AB Pre-eclampsia and eclampsia are hypertensive disorders of pregnancy associated with maternal mortality and fetal complications. Pre-eclampsia is defined as new onset of maternal hypertension after 20 weeks gestation and proteinuria. The term eclampsia is used when the central nervous system (CNS) is involved, which surfaces as new onset of seizures in the setting of pre-eclampsia. Pre-eclampsia occurs in 3%–4% of pregnancies with an increasing incidence in the United States. Women with chronic conditions associated with endothelial dysfunction (chronic hypertension, diabetes mellitus, and renal disease) are at an increased risk for developing pre-eclampsia during pregnancy. Advanced maternal age, nulliparity, obesity, and African American race are also considered to be risk factors.