RT Book, Section A1 Potestio, Christopher A1 Nguyen, Vinh A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1135741245 T1 Disseminated Intravascular Coagulation T2 Anesthesiology Core Review: Part Two Advanced Exam YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259641770 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1135741245 RD 2024/04/16 AB Disseminated intravascular coagulation (DIC) is a disease process in which the entire coagulation pathway undergoes activation. All critically ill patients undergo some degree of coagulation activation due to inflammation and hemodynamic changes. In some cases, the balance of anticoagulations and procoagulants is tipped in favor of procoagulants, leading to DIC. No single laboratory test defines DIC, and there is no gold standard for diagnosis. Laboratory assays allow practitioners to define the state of the disease and assess the risk of bleeding and thrombosis. Table 98-1 lists laboratory values that assist in the diagnosis and management of DIC.