RT Book, Section A1 Nguyen, Vinh A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1135741217 T1 Congenital and Acquired Factor Deficiencies T2 Anesthesiology Core Review: Part Two Advanced Exam YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259641770 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1135741217 RD 2024/04/19 AB Hemostasis relies on an intact coagulation cascade for adequate clotting. Any disruption or deficiencies in the cascade can lead to severe and devastating clinical complications. The classic plasma-mediated hemostasis has been depicted as two independent pathways—the intrinsic and extrinsic pathways. Together, they will lead into a common pathway to generate thrombin and ultimately fibrin monomers for clotting.