RT Book, Section A1 Silver, Polyanna A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1135740868 T1 Pathophysiology of Renal Disease T2 Anesthesiology Core Review: Part Two Advanced Exam YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259641770 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1135740868 RD 2022/05/26 AB Acute Kidney Injury (AKI), formerly known as acute renal failure, is characterized by deterioration of renal function over hours to days, resulting in failure of the kidneys to excrete nitrogenous waste products and to maintain homeostasis. AKI affects 5%–7% of all hospitalized patients. The overall mortality rates for AKI is greater than 20% and, once dialysis is required, mortality rates rise to greater than 50%. Only 15% of patients developing AKI fully recover renal function. Survivors are left with either stable or progressive renal insufficiency, with many being at risk for developing a chronic kidney failure later in life.