RT Book, Section A1 Lobaugh, Lauren A1 Freeman, Brian S. A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1135740176 T1 Regurgitant Valvular Disease T2 Anesthesiology Core Review: Part Two Advanced Exam YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259641770 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1135740176 RD 2024/04/16 AB Chronic aortic insufficiency (AI) is typically the result of congenital conditions such as a bicuspid aortic valve, rheumatic disease, connective tissue disorders (e.g., Marfan’s syndrome), or cystic medical necrosis. Acute AI is rarer and carries a poor prognosis. Aortic dissections, trauma, and bacterial endocarditis can lead to acute aortic insufficiency. Both processes lead to malcoaptation of the aortic valve leaflets by causing abnormalities in the leaflets themselves or dilation of the AV annulus, the aortic root, or both.