RT Book, Section A1 Mueller, Joseph A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1135739726 T1 One-Lung Ventilation T2 Anesthesiology Core Review: Part Two Advanced Exam YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259641770 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1135739726 RD 2024/04/19 AB Lung separation to prevent pus or blood spillage from an infected or bleeding source is an absolute indication for OLV. Bilateral contamination may lead to life-threatening infection or inability to oxygenate or ventilate a patient. Fistulas may provide a low resistance pathway for positive-pressure ventilation (PPV) that compromises alveolar ventilation. Large cysts or bullae are susceptible to rupture under PPV. Many thoracic procedures involving the lungs or mediastinum are technically difficult and benefit from OLV. Lung isolation assists with optimal surgical exposure and a “quiet” surgical field. OLV can also help minimize lung trauma from retractors and manipulation.