RT Book, Section A1 Pitts-Kiefer, M. Alexander A1 De Marchi, Lorenzo A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1135739655 T1 Restrictive Lung Disease T2 Anesthesiology Core Review: Part Two Advanced Exam YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259641770 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1135739655 RD 2024/04/19 AB Restrictive pulmonary disease is characterized by reductions in lung volumes. Compared to disorders consistent with an obstructive pulmonary pattern, there is no increase in airway resistance and measures of airflow are within normal limits. Pulmonary function tests (PFTs) in patients with restrictive disease will show a reduction in total lung capacity (TLC) leading to reductions in both forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC). Because both values are reduced, the FEV1/FVC ratio remains normal (Figure 46-1). The flow-volume loop is general normal, but demonstrates reduced lung volumes (Figure 46-2). FRC is decreased. Total pulmonary compliance is also reduced. Patients with restrictive disease increase their work of breathing by taking slow, deep breaths.