RT Book, Section A1 Freeman, Brian S. A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1135739375 T1 Transsphenoidal Hypophysectomy T2 Anesthesiology Core Review: Part Two Advanced Exam YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259641770 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1135739375 RD 2024/04/25 AB Hypophysectomy, the removal of the pituitary gland, can be performed through a number of surgical approaches. For large tumors that have extended beyond the pituitary fossa, a bifrontal craniotomy is often necessary. Most pituitary tumors lie within the sella (or immediate suprasellar area) and are therefore amenable to excision via the transsphenoidal technique. Transsphenoidal hypophysectomy requires the use of a microscope or endoscope to enter the sella through the nose and sphenoid sinus. Advantages include rapid midline access to the sella with minimal risk of brain injury or bleeding. The incision may be made in the back wall of the noise, along the front of the nasal septum, or under the upper lip. Endoscopy enables excellent tumor visualization, opening of the diaphragmatic sellae, and decompression of the optic nerve.