RT Book, Section A1 Monahan, Christopher A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1135738857 T1 Intracranial Pressure T2 Anesthesiology Core Review: Part Two Advanced Exam YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259641770 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1135738857 RD 2024/04/18 AB Intracranial volume largely determines intracranial pressure (ICP), since the skull fixes the volume. The three intracranial components are brain, cerebrospinal fluid (CSF), and blood. The brain itself, composed of cellular components and water, comprises roughly 90% of intracranial volume and may expand from tumor growth or edema. CSF accounts for roughly 5% of intracranial volume and may expand with hydrocephalus. Lastly, blood accounts for approximately 5% of intracranial volume. Expansion of the blood compartment occurs with cerebral hemorrhage or increased cerebral blood flow (CBF) as a result of cerebral vasodilation.