RT Book, Section
A1 Levin, Ellis R.
A1 Hammes, Stephen R.
A2 Brunton, Laurence L.
A2 Chabner, Bruce A.
A2 Knollmann, Björn C.
SR Print(0)
ID 1127869442
T1 Estrogens and Progestins
T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 12e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071624428
LK accessanesthesiology.mhmedical.com/content.aspx?aid=1127869442
RD 2023/10/01
AB Estrogens  and  progestins  are  endogenous  hormones  that  produce  numerous  physiological  actions.  In  women,  these  include  developmental  effects,  neuroendocrine  actions  involved  in  the  control  of  ovulation,  the  cyclical  preparation  of  the  reproductive  tract  for  fertilization  and  implantation,  and  major  actions  on  mineral,  carbohydrate,  protein,  and  lipid  metabolism.  Estrogens  also  have  important  actions  in  males,  including  effects  on  bone,  spermatogenesis,  and  behavior.  The  biosynthesis,  biotransformation,  and  disposition  of  estrogens  and  progestins  are  well  established.  Two  well-characterized  receptors  are  present  for  each  hormone,  and  there  is  evidence  that  the  receptors  mediate  biological  actions  in  both  the  unliganded  and  steroid  hormone-liganded  states.