TY - CHAP M1 - Book, Section TI - Antiemetics A1 - Manchester, Amy K. A1 - Gan, Tong J. A2 - Johnson, Ken B. PY - 2015 T2 - Clinical Pharmacology for Anesthesiology AB - Postoperative nausea and vomiting (PONV) is the most common complication associated with anesthesia and surgery, occurring in approximately one-third of all patients and up to 70% of “high-risk” patients.1 PONV is a cause of great distress for patients, and in addition to creating a highly unpleasant experience of discomfort, it can lead to a variety of unintended consequences such as delayed discharge, wound dehiscence, dehydration, tearing of sutures, and potential pulmonary aspiration, all of which serve to greatly increase medical costs.2 Understanding the various mechanisms involved in PONV is critical for optimizing the prophylaxis and treatment of this unwanted side effect of anesthesia. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1103964128 ER -