TY - CHAP M1 - Book, Section TI - Antithrombotic Drugs A1 - Nguyen, Vinh A2 - Freeman, Brian S. A2 - Berger, Jeffrey S. PY - 2014 T2 - Anesthesiology Core Review: Part One Basic Exam AB - Obstruction of arterial or venous blood flow to vital vessels can have a dramatic impact on mortality and morbidity. Prior to thrombolytic agents, open surgical procedures were preformed to restore vessel patency and preserve vital organs. Antithrombotic agents are currently the mainstay therapy for achieving fibrinolysis during an acute ischemic event. Indications include acute myocardial infarction, ischemic stroke, deep venous thrombosis, pulmonary embolism, limb ischemia, and central line occlusion. Therefore, antithrombotic agents are used to target these blood clots directly using a catheter-directed thrombolysis or a systemic approach to dissolve the existing obstruction. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/01 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1102570060 ER -