TY - CHAP M1 - Book, Section TI - Alkaptonuria (AKU) A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Marciniak, Bruno A1 - Dalens, Bernard J. PY - 2006 T2 - Syndromes: Rapid Recognition and Perioperative Implications AB - Deficiency of homogentisic acid oxidase leads to discoloration and staining of tissues. Sudden dark urine should alert the clinician of the possible presence of homogentisic acid. Valvular heart disease and myocardial ischemia may occur in adults. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=58062201 ER -