TY - CHAP M1 - Book, Section TI - Chapter 118. Brain Death and Organ Donation A1 - Go, Ronaldo Collo A1 - Kohli-Seth, Roopa A2 - Atchabahian, Arthur A2 - Gupta, Ruchir PY - 2013 T2 - The Anesthesia Guide AB - Acute CNS catastrophic event excluding acid-base, circulatory, electrolyte, hemodynamic disturbances, and no evidence of poisoning or hypothermiaClinical examination: absent brainstem function; spinal cord and peripheral nerve reflexes may occurClinical exam repeated after 6 hours in patients over 1-year-oldApnea test performed after second clinical examinationPatient disconnected from ventilator and placed on 6 L/min O2 by T-pieceSpontaneous respirations within 8 to 15 minutes = negative apnea testNo spontaneous respirations while PCO2 ≥ 60 or increase in PCO2 ≥ 20 from baseline = positiveClinical examination and positive apnea test are sufficient to affirm brain death SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/10/10 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=57262283 ER -