TY  - CHAP
M1  - Book, Section
TI  - Chapter 101. Craniotomy
A1  - Goettel, Nicolai
A2  - Atchabahian, Arthur
A2  - Gupta, Ruchir
PY  - 2013
T2  - The Anesthesia Guide
AB  - Table  Graphic  Jump  Location|Download  (.pdf)|PrintCranial  contentsSkull  represents  a  closed,  non-expandable  unit  containing  three  compartments  (CBV,  CSF,  brain  tissue)  determining  ICPAny  increase  in  volume  of  one  of  the  cranial  compartments  must  be  compensated  by  a  decrease  in  volume  of  another  to  maintain  the  pressure  equilibrium  (Monro-Kellie  doctrine)Small  increases  in  intracranial  volume  will  lead  to  large  increases  in  ICP  once  this  buffer  mechanism  is  exhausted  (Figure  101-1),  compromising  CBVBlood  and  cerebral  vasculature  (cerebral  blood  volume,  CBV)Two  carotid  arteries  (70%  blood  flow  to  the  brain)Two  vertebral  arteries  (30%  blood  flow  to  the  brain)Arterial  anastomosis  through  Willis  circle  and  anastomosis  with  external  carotid  arteries  through  branches  of  facial  and  ophthalmic  arteriesVenous  return  through  cortical  veins  (superficial  drainage),  and  basilar  and  ventricular  veins  (profound  drainage)  essentially  into  the  IJ  veinsCerebro-spinal  fluid  (CSF)Produced  by  choroid  plexus,  reabsorbed  by  granules  of  PacchioniTotal  volume  of  CSF  in  the  adult:  140–270  mLProduction  of  0.2–0.7  mL/min  or  600–700  mL/day  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessanesthesiology.mhmedical.com/content.aspx?aid=57262024
ER  -