TY - CHAP M1 - Book, Section TI - Chapter 65. Fluid Management in the Ventilated Patient A1 - Bersten, Andrew D. A2 - Tobin, Martin J. PY - 2013 T2 - Principles and Practice of Mechanical Ventilation, 3e AB - Fluid management during mechanical ventilation is complicated by both the influence of positive-airway pressure on normal homeostatic control of bodily fluids, and the interaction of mechanical ventilation with fluid status. Hypovolemia may lead to hemodynamic intolerance of positive-airway pressure, and fluid overload may result in both impaired gas exchange and respiratory mechanics and deleterious systemic effects. In patients with acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS), positive fluid balance has been associated with both fewer ventilator-free days, and longer intensive care unit (ICU) stay, and with mortality in prospective randomized1 and observational2 studies, respectively. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/18 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=57081737 ER -