TY - CHAP M1 - Book, Section TI - Chapter 84. Cognitive Dysfunction after Anesthesia and Surgery A1 - Hathaway, Jessica A. A1 - Newman, Mark F. A1 - Mathew, Joseph P. A2 - Longnecker, David E. A2 - Brown, David L. A2 - Newman, Mark F. A2 - Zapol, Warren M. PY - 2012 T2 - Anesthesiology, 2e AB - Cognition represents key processes of memory, attention, perception, problem solving, and mental imagery that define who we are as individuals.Cognitive functioning is key to the activities of daily living and our overall quality of life.Cognitive assessment occurs by a number of well-validated measurements outlined in the field of neuropsychology. Assessment of cognitive functioning in the perioperative period is often less complete than normal; however, understanding what is measured by each individual test and how these values change over time is essential in understanding the implications to our patients of perioperative cognitive decline.The incidence of postoperative cognitive dysfunction varies based on the sensitivity of the tests used and the time frame for evaluation. Correlation with appropriate control groups gives the best idea of the relative impact of surgery and anesthesia on changes in cognition and quality of life.The etiology of cognitive function and/or cognitive dysfunction is complex and is associated with the severity of diseases including atherosclerosis and diabetes, as well as with surgery and anesthesia. The effect of anesthetic agents on short- and long-term cognition is controversial.New studies indicate an association between patient factors including disease severity and genetic predisposition, and perioperative cognitive decline.Determining the risks of perioperative cognitive decline enhances the probability of developing interventions to reduce cognitive decline and thus improve quality of life after surgery. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=56655336 ER -