TY - CHAP M1 - Book, Section TI - Chapter 69. Bleeding Disorders A1 - Baron, Joseph M. A1 - Baron, Beverly W. A2 - Hall, Jesse B. A2 - Schmidt, Gregory A. A2 - Wood, Lawrence D.H. PY - 2005 T2 - Principles of Critical Care, 3e AB - Assessment of the patient with a bleeding diathesis requires careful history-taking and bedside evaluation and comprehensive baseline coagulation testing.Uncomplicated vascular injury related to trauma or surgery should be eliminated as the primary cause of bleeding before the possibility of a coagulopathy is invoked.Consideration of coagulation abnormalities should include vascular disorders, platelet problems, impairment of the fibrin generation cascade, and excessive fibrinolytic activity.Disseminated intravascular coagulation may present with either thrombotic or bleeding problems. Awareness of the possibility of this diagnosis and prompt, appropriate laboratory confirmation may improve treatment selection and outcome.Invasive procedures in critically ill patients with coagulopathies need to be performed with special caution to prevent complications. Some guidelines are presented. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2023/06/09 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=2293407 ER -