TY - CHAP M1 - Book, Section TI - Chapter 54. Life-Threatening Infections of the Head, Neck, and Upper Respiratory Tract A1 - Chow, Anthony W. A2 - Hall, Jesse B. A2 - Schmidt, Gregory A. A2 - Wood, Lawrence D.H. PY - 2005 T2 - Principles of Critical Care, 3e AB - A thorough knowledge of the fascial relations and the potential anatomic routes of infection is a prerequisite to optimal management of deep neck infections.The microbial etiology of deep infections of the head and neck is complex and typically polymicrobial. Anaerobes generally outnumber aerobes by a factor of 10:1.The development of marked asymmetry in the course of a submandibular space infection should be viewed with great concern because it may be indicative of extension to the lateral pharyngeal space.In immunocompromised patients, the classic manifestations of infection, such as edema and fluctuance at the local site and features of systemic toxicity, may be absent.Penicillin with metronidazole is the antibiotic regimen of choice for odontogenic deep neck infections, but immunocompromised patients require a broader spectrum against organisms such as Staphylococcus aureus and enteric gram-negative rods.Chronic sinusitis, otitis, and mastoiditis are the most important causes of parameningeal infection and intracranial suppuration. Computed tomography is the single neuroimaging technique proved to be the most useful for the diagnosis of these conditions. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2023/09/29 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=2291675 ER -