TY - CHAP M1 - Book, Section TI - General Principles of Antimicrobial Therapy A1 - MacDougall, Conan A2 - Brunton, Laurence L. A2 - Knollmann, Björn C. PY - 2023 T2 - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition AB - AbbreviationsABC: ATP binding cassetteAUC: area under the Cp-time curveCCR5: chemokine receptor type 5CD4: T-helper cellsCMV: cytomegalovirusCp: plasma concentrationCPmax: peak plasma concentrationCYP: cytochrome P450DHFR: dihydrofolate reductaseDHPS: dihydropteroate synthaseE: effectEC: effective concentrationELF: epithelial lining fluidEmax: maximal effectHIV: human immunodeficiency virusIC: inhibitory concentrationMALDI-TOF MS: matrix-assisted laser desorption/ionization time-of-flight mass spectrometryMEC: minimum effective concentrationMIC: minimum inhibitory concentrationPAE: postantibiotic effectPCR: polymerase chain reactionPK/PD: pharmacokinetics-pharmacodynamicsPrEP: preexposure prophylaxisrpoB: RNA polymerase SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1193238656 ER -