TY - CHAP M1 - Book, Section TI - Anesthesia for Thoracic Procedures A1 - Cossu, Anne E. A1 - Hardacker, Doris M. A2 - Ellinas, Herodotos A2 - Matthes, Kai A2 - Alrayashi, Walid A2 - Bilge, Aykut PY - 2021 T2 - Clinical Pediatric Anesthesiology AB - FOCUS POINTS1.Type II pneumocytes develop at 24 to 26 weeks of gestation and begin producing surfactant. Eight to ten percent of the number of adult alveoli are present at birthInfants and children have reduced functional residual capacity (FRC) and higher oxygen consumption (6 to 8 ml/kg/min) rendering them susceptible to faster oxygen desaturation.Etiologies for increased ventilation to perfusion (V/Q) mismatch during thoracic surgery include lateral positioning, general anesthesia and blunting of hypoxic pulmonary vasoconstriction, mechanical ventilation and surgical manipulation or single-lung ventilation.One-lung ventilation (OLV) can be achieved utilizing single lumen endotracheal tubes inserted into the main stem bronchus, endobronchial blockers, Univent tubes or double lumen tubes dependent on the size of the patient.Management of hypoxemia during OLV includes 100% oxygen, continuous positive airway pressure (CPAP) to the nondependent lung, positive end-expiratory pressure (PEEP) to the dependent lung, double lung ventilation and in extremis occlusion of the pulmonary artery to the operative lung.Thoracic and mediastinal masses are lesions that may cause airway compromise prior to or during a procedure under anesthesia. Thorough preoperative evaluation that includes review of echocardiogram, available imaging, and symptoms allow for a safer anesthetic. Spontaneous ventilation with min sedation may be the anesthetic of choice. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/24 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1176458046 ER -