TY - CHAP M1 - Book, Section TI - Vasoactive Medications A1 - Voulgarelis, Stylianos A2 - Ellinas, Herodotos A2 - Matthes, Kai A2 - Alrayashi, Walid A2 - Bilge, Aykut PY - 2021 T2 - Clinical Pediatric Anesthesiology AB - FOCUS POINTSThe increased metabolic rate of children comparing to adults requires a different selection of vasoactive drugs to restore and maintain the oxygen delivery to the tissues and support the circulation during periods of stress or sepsis.Phenylephrine has a very narrow therapeutic spectrum in the pediatric population, mostly limited for patients with tetralogy of Fallot (TOF) and hypertrophic obstructive cardiomyopathy (HOCM)Milrinone is used in pediatric patients with congenital heart disease, cardiomyopathy, and heart failure and in patients with increased pulmonary vascular resistance (PVR).Dopamine is still used to improve tissue perfusion and urine output in neonates and premature infants.Newborn myocardium contractility depends significantly on serum calcium levels. Hypocalcemia needs to be promptly identified and corrected. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/18 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1176457305 ER -