TY - CHAP M1 - Book, Section TI - Physiological Aspects A1 - Chandran, Neethu A1 - Kiss, Edgar E. A2 - Ellinas, Herodotos A2 - Matthes, Kai A2 - Alrayashi, Walid A2 - Bilge, Aykut PY - 2021 T2 - Clinical Pediatric Anesthesiology AB - FOCUS POINTSThe posterior fontanelle closes around 6 months of age and the anterior fontanelle around 12 to 18 months. Therefore, a slow increase in intracranial volume prior to cranial suture fusion can be compensated by an increase in head circumference.Signs of intracranial hypertension differ in adults compared to children. Typical signs of high intracranial pressure (ICP) include increased irritability, headaches, decreased feeding, and morning emesis.CMRO2 in children increases to 5.2 mL/100 g/min making them more susceptible to hypoxemia, contrary to neonates who have a lower CMRO2 at 3.5 mL/100 g/min making them relatively tolerant to hypoxemia.By the age of 5, children have the normal adult volume of cerebrospinal fluid (CSF) which is 150 mL. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1176456663 ER -