TY  - CHAP
M1  - Book, Section
TI  - Aortic Valve Disease
A1  - Wasnick, John D.
A1  - Nicoara, Alina
PY  - 2019
T2  - Cardiac Anesthesia and Transesophageal Echocardiography, 2e
AB  - The  aortic  valve  (AV)  is  the  gateway  through  which  the  stroke  volume  is  ejected  from  the  left  ventricle  (LV)  into  the  systemic  circulation.  Should  the  gateway  be  narrowed  as  in  aortic  stenosis  (AS),  the  LV  hypertrophies  concentrically  and  ejects  the  stroke  volume  through  the  reduced  aortic  valve  orifice.  The  thickened  heart  muscle  and  the  increased  work  of  ventricular  ejection  augments  the  oxygen  demand  of  the  ventricle,  which  if  not  met,  results  in  myocardial  ischemia.  On  the  other  hand,  if  the  valve  is  incompetent  resulting  in  aortic  insufficiency  or  regurgitation  (AR),  the  left  ventricle  dilates  and  develops  eccentric  hypertrophy  to  accommodate  the  increased  volume  filling  the  LV  cavity  during  diastole.  When  the  AV  is  incompetent,  diastolic  pressure  falls  and  coronary  perfusion  pressure  (CPP)  decreases,  increasing  the  risk  of  ischemia.  Providing  anesthesia  for  patients  with  AV  disease  undergoing  aortic  valve  surgery  or  noncardiac  procedures  can  be  challenging.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2022/12/06
UR  - accessanesthesiology.mhmedical.com/content.aspx?aid=1166980480
ER  -