TY - CHAP M1 - Book, Section TI - Aortic Valve Disease A1 - Wasnick, John D. A1 - Nicoara, Alina PY - 2019 T2 - Cardiac Anesthesia and Transesophageal Echocardiography, 2e AB - The aortic valve (AV) is the gateway through which the stroke volume is ejected from the left ventricle (LV) into the systemic circulation. Should the gateway be narrowed as in aortic stenosis (AS), the LV hypertrophies concentrically and ejects the stroke volume through the reduced aortic valve orifice. The thickened heart muscle and the increased work of ventricular ejection augments the oxygen demand of the ventricle, which if not met, results in myocardial ischemia. On the other hand, if the valve is incompetent resulting in aortic insufficiency or regurgitation (AR), the left ventricle dilates and develops eccentric hypertrophy to accommodate the increased volume filling the LV cavity during diastole. When the AV is incompetent, diastolic pressure falls and coronary perfusion pressure (CPP) decreases, increasing the risk of ischemia. Providing anesthesia for patients with AV disease undergoing aortic valve surgery or noncardiac procedures can be challenging. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2021/02/24 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1166980480 ER -