TY - CHAP M1 - Book, Section TI - Xeroderma Pigmentosum (XP) A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - A syndrome characterized by a defect in ultraviolet radiation-induced deoxyribonucleic acid (DNA) repair mechanisms and by a severe sensitivity to all sources of ultraviolet radiation (especially sunlight). XP is categorized into seven complementation groups according to the capacity of the body to repair DNA (XPA to XPG) and XPV (variant, second decade of life). The DNA damage is cumulative and irreversible. Skin, eyes, and nervous system affected depending on group. Major risk of skin cancers. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1164088446 ER -