TY - CHAP M1 - Book, Section TI - Wohlfart-Kugelberg-Welander Syndrome A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is an autosomal recessive juvenile spinal muscular atrophy characterized by slowly progressive muscular weakness and atrophy of the upper and lower limbs. It is caused by the degeneration of anterior horn cells (spinal motor neurons). The onset of the disease is during childhood, particularly between the ages of 2 and 17 years. Early symptoms consist of atrophy and weakness of the proximal muscle of the extremities (mainly legs), followed by thoracic muscles. Should not be confused with muscular dystrophy syndromes. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1164088279 ER -