TY - CHAP M1 - Book, Section TI - Myoadenylate Deaminase Deficiency A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is an inherited or secondarily acquired disorder of muscle purine nucleotide metabolism. The clinical manifestations include exercise-induced myopathy, post-exertional muscle weakness or cramping, prolonged fatigue after exertion, and limping infant caused by benign congenital hypotonia. Generalized muscle pair is often manifested. There is evidence that patients with myoadenylate deaminase deficiency (and the carrier as well) may be at an increased risk of malignant hyperthermia (MH) when subjected to anesthesia. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1164079764 ER -