TY - CHAP M1 - Book, Section TI - Lyme Disease A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is an infectious disease caused by a spirochete with significant immune response possibly leading to neurologic problems. Most patients consult within 7 days of the initial tick bite. The incubation period varies between 3 and 30 days. The skin lesion is characteristically an annular erythematous lesion greater than 5 cm in diameter that slowly increased in size and is painless and nonpruritic. The skin lesion is called erythema migrans and often appears as a bull’s-eye shape with a large hallow around. The second stage includes the formation of large blisters and purple skin masses. Other clinical features include fatigue, arthralgia, headache, and low-grade fever. With time, cardiovascular manifestations (AV blocks, tachycardia) and potentially severe neurological complications (encephalopathy, aseptic meningitis, cranial neuropathy—especially the facial nerve, and sensorimotor neuropathy) are seen within the first 3 months. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1164077335 ER -