TY - CHAP M1 - Book, Section TI - Hereditary Sensory and Autonomic Neuropathy Type I (HSAN I) A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - Genetic neurodegenerative disorder characterized by a loss of sensations, especially in the lower extremities, leading to perforating skin ulceration and bone destruction as a result of abnormal functioning of the autonomic nervous system. Type I is the most common form among the five types of HSAN. The disease usually starts during early adolescence or adulthood. The disease is characterized by the loss of pain sensation mainly in the distal parts of the lower limbs such as feet and lower legs. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1164072658 ER -