TY - CHAP M1 - Book, Section TI - Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy A1 - Gumbo, Tawanda A2 - Brunton, Laurence L. A2 - Hilal-Dandan, Randa A2 - Knollmann, Björn C. PY - 2017 T2 - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13e AB - Mycobacteria have caused epic diseases: TB and leprosy have terrorized humankind since antiquity. Although the burden of leprosy has decreased, TB is still the most important infectious killer of humans. Mycobacterium abscessus has now been called a new “antibiotic” nightmare because of its tenacity, lack of response to combination antibiotics, and a nearly universal propensity to develop acquired drug resistance. Mycobacterium avium-intracellulare (or MAC) infection continues to be difficult to treat, mainly due to three natural barriers: SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1162545357 ER -