TY - CHAP M1 - Book, Section TI - Evaluation of the Patient with Multiorgan Dysfunction Syndrome A1 - Kwo, Jean A1 - Wang, Binbin A1 - Hellman, Judith A2 - Longnecker, David E. A2 - Mackey, Sean C. A2 - Newman, Mark F. A2 - Sandberg, Warren S. A2 - Zapol, Warren M. PY - 2017 T2 - Anesthesiology, 3e AB - KEY POINTSMultiorgan dysfunction syndrome (MODS) is common in critically ill patients and associated with a high mortality rate.There are many underlying etiologies of MODS. In the overall intensive care unit (ICU) population, sepsis is the most common cause of MODS.MODS is characterized by dysfunction of two or more organs or systems.Inflammation and microvascular abnormalities are involved in the development of MODS.Therapies for MODS should target the underlying cause, support the patient, and correct the physiologic and metabolic derangements caused by organ dysfunction.Patients with MODS often require surgery and other invasive procedures.Preoperative optimization should be dictated by the affected organs and the severity of physiologic and metabolic derangements. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1144134677 ER -