TY - CHAP M1 - Book, Section TI - Neurobiologic Mechanisms of Nociception A1 - Liu, Qing A1 - Gold, Michael S. A2 - Hadzic, Admir PY - 2017 T2 - Hadzic's Textbook of Regional Anesthesia and Acute Pain Management, 2e AB - Optimal postoperative pain management is a clinical priority because poorly managed pain may delay functional recovery from surgery and /or lead to chronic pain.1 Nevertheless, despite considerable effort to improve postoperative pain management, one third of patients continue to suffer from moderate to severe pain.2 The lack of consistently effective analgesics devoid of deleterious consequences remains one of the main causes of the inadequacy of postoperative pain management. Therefore, identification of novel therapeutic targets and more effective management strategies remain high priorities in pain research. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1141738309 ER -