TY - CHAP M1 - Book, Section TI - Neuraxial Anesthesia & Peripheral Nerve Blocks in Patients on Anticoagulants A1 - Benzon, Honorio T. A1 - Jabri, Rasha S. A1 - Zundert, Tom C. Van A2 - Hadzic, Admir PY - 2017 T2 - Hadzic's Textbook of Regional Anesthesia and Acute Pain Management, 2e AB - Intraspinal hematoma is a relatively rare condition resulting from a variety of causes. Traumatic causes include lumbar puncture and neuraxial anesthesia. It is more likely to occur in anticoagulated or thrombocytopenic patients, patients with neoplastic disease, or in those with liver disease or alcoholism. Approximately one-quarter to one-third of all cases are associated with anticoagulation therapy. The risk of intraspinal hematoma formation after administration of neuraxial anesthesia and analgesia is increased in patients who have received anticoagulant therapy or have a coagulation disorder.1 For this reason, neuraxial anesthesia is often contraindicated in the presence of a coagulopathy. Other risk factors for the development of epidural or spinal hematoma include technical difficulty (multiple attempts) in the performance of the neuraxial procedures due to anatomic abnormalities of the spine and multiple or bloody punctures. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1141736664 ER -