TY - CHAP M1 - Book, Section TI - Targeted Temperature Management After Cardiac Arrest A1 - Friedman, Oren A. A2 - Oropello, John M. A2 - Pastores, Stephen M. A2 - Kvetan, Vladimir PY - 1 T2 - Critical Care AB - KEY POINTSTargeted temperature management (TTM) refers to the global practice of controlling temperature after cardiac arrest. Mild therapeutic hypothermia refers to a temperature between 32°C and 34°C.The positive effects of TTM postarrest are believed to be related to its effects in suppressing the whole body reperfusion injury, and preventing exacerbation of that injury by hyperthermia.Device therapy for TTM can be divided into surface cooling and invasive technology.The three phases of TTM are induction, maintenance, and rewarming.There is no consensus on the optimal rate of rewarming although it is recognized that uncontrolled or rapid rewarming can lead to vasodilation, hemodynamic instability, and dangerous electrolyte shifts.The lack of pupillary reflexes 3 days postcardiac arrest, the presence of myoclonic status epilepticus (MSE), and the absence of somatosensory-evoked potentials (SSEPs) all very likely portend an extremely poor prognosis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/15 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1136412580 ER -