TY - CHAP M1 - Book, Section TI - Restrictive Lung Disease A1 - Pitts-Kiefer, M. Alexander A1 - De Marchi, Lorenzo A2 - Freeman, Brian S. A2 - Berger, Jeffrey S. PY - 2016 T2 - Anesthesiology Core Review: Part Two Advanced Exam AB - Restrictive pulmonary disease is characterized by reductions in lung volumes. Compared to disorders consistent with an obstructive pulmonary pattern, there is no increase in airway resistance and measures of airflow are within normal limits. Pulmonary function tests (PFTs) in patients with restrictive disease will show a reduction in total lung capacity (TLC) leading to reductions in both forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC). Because both values are reduced, the FEV1/FVC ratio remains normal (Figure 46-1). The flow-volume loop is general normal, but demonstrates reduced lung volumes (Figure 46-2). FRC is decreased. Total pulmonary compliance is also reduced. Patients with restrictive disease increase their work of breathing by taking slow, deep breaths. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1135739655 ER -