TY - CHAP M1 - Book, Section TI - Anaphylaxis During Pregnancy A1 - Chaudhuri, Kal A2 - Santos, Alan C. A2 - Epstein, Jonathan N. A2 - Chaudhuri, Kallol Y1 - 2015 N1 - T2 - Obstetric Anesthesia AB - The word anaphylaxis (ana: backward; phylaxis: guard, or “against protection”) was coined by Paul Portier and Charles Richet, two scientists who unexpectedly induced acute anaphylaxis in their experimental dogs during an attempt to produce vaccines for prophylaxis against a toxin (actinotoxin) from a sea anemone, Actiniasulcata.1 Anaphylaxis is a severe, life-threatening, systemic event caused by immediate hypersensitivity reaction. Although it is relatively infrequent during pregnancy, the potentially fatal effects on the mother and the unborn baby warrant prompt recognition and immediate management. Severe anaphylaxis, in general, affects 1 to 3 per 10,000 population,2 but the incidence during anesthesia is reported to range from as high as 1 in 4000 to 1 in 25,000.3 The prevalence of anaphylaxis in pregnant patients is approximately 3 per 100,000 deliveries.4 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1108523386 ER -