TY - CHAP M1 - Book, Section TI - Opioid and Benzodiazipine Reversal Agents A1 - Call, Tyler A2 - Johnson, Ken B. Y1 - 2015 N1 - T2 - Clinical Pharmacology for Anesthesiology AB - Opioid and benzodiazepine antagonists are an important component of an anesthesiologists’ armamentarium. Anesthesiologists rely on these agents for rapid reversal of adverse effects such as respiratory depression and loss of responsiveness. This may be especially important in the context of restoring ventilation in hypoxic patients either by antagonizing the ventilatory depressant effect of opioids or antagonizing the sedating properties of benzodiazepines so that patients can be prompted to breathe. Furthermore, select antagonists may also play an important role in other pathologic conditions, including tumor progression in selected types of cancer. This chapter will provide a brief overview of commonly used opioid and benzodiazepine antagonists. A summary of each reversal agent is presented in Table 7–1. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1103963471 ER -