TY - CHAP M1 - Book, Section TI - Spinal Anesthesia A1 - Lopatin, Jonah A1 - Jivan, Kuntal A2 - Freeman, Brian S. A2 - Berger, Jeffrey S. Y1 - 2014 N1 - T2 - Anesthesiology Core Review: Part One Basic Exam AB - The epidural space lies between the walls of the vertebral canal and the meninges. The meninges are composed of three distinct layers (dura, arachnoid, and pia mater) that are continuous cephalad with the cranial meninges. Dura mater, the outermost layer, extends from the foramen magnum to S2 in adults where it fuses with the filum terminale. The innermost layer of dura mater is highly vascular and serves as the principal route for elimination of drugs in the epidural and subarachnoid space. The arachnoid mater lies deep in the dura and serves as a tight barrier, separating the spinal cord from the epidural space. A potential space exists between the dura and arachnoid mater. The pia mater is the deepest layer of the spinal meninges and adheres to the spinal cord. The subarachnoid space lies between the arachnoid and pia mater, and contains the cerebrospinal fluid (CSF). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/24 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1102567475 ER -