TY  - CHAP
M1  - Book, Section
TI  - Drug Tolerance and Tachyphylaxis
A1  - Vashishta, Rishi
A1  - Berrigan, Michael J.
A2  - Freeman, Brian S.
A2  - Berger, Jeffrey S.
Y1  - 2014
N1  - 
T2  - Anesthesiology Core Review: Part One Basic Exam
AB  - Physiologic  tolerance,  or  desensitization,  is  well  described  in  clinical  pharmacology.  It  is  defined  by  progressively  diminished  response  to  drug  at  a  certain  dose  following  repeated  exposure,  and  requiring  increasing  dosages  to  achieve  the  desired  effect  on  subsequent  administrations.  Drug  tolerance  refers  to  changes  in  the  potency  (higher  effective  dose  required),  the  effectiveness  (decreased  maximal  effect),  or  both  aspects  of  the  drug.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/23
UR  - accessanesthesiology.mhmedical.com/content.aspx?aid=1102566806
ER  -