TY - CHAP M1 - Book, Section TI - Chapter 74. Evaluation of the Patient with Multiple Organ Dysfunction Syndrome A1 - Wang, Binbin A1 - Kwo, Jean A1 - Hellman, Judith A2 - Longnecker, David E. A2 - Brown, David L. A2 - Newman, Mark F. A2 - Zapol, Warren M. Y1 - 2012 N1 - T2 - Anesthesiology, 2e AB - Multiple organ dysfunction syndrome (MODS) is common in critically ill patients and associated with a high mortality rate.There are many underlying etiologies of MODS. In the overall intensive care unit (ICU) population, sepsis is the most common cause of MODS.MODS is characterized by dysfunction of 2 or more organs or systems.Inflammation and microvascular abnormalities are involved in the development of MODS.Therapies for MODS should target the underlying cause, supporting the patient and correcting the physiologic and metabolic derangements caused by dysfunction of the organs and systems.Patients with MODS often require surgery and other invasive procedures.Whenever possible, optimize MODS patients preoperatively.Methods of optimization are dictated by the affected organs and the severity of physiologic and metabolic derangements. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=56651870 ER -