TY  - CHAP
M1  - Book, Section
TI  - Chapter 111. Hyperthermia
A1  - Zimmerman, Janice L.
A1  - Hanania, Nicola A.
A2  - Hall, Jesse B.
A2  - Schmidt, Gregory A.
A2  - Wood, Lawrence D.H.
Y1  - 2005
N1  - 
T2  - Principles of Critical Care, 3e
AB  - Heat  stroke  is  distinguished  from  less  severe  forms  of  environmental  hyperthermia  by  higher  body  temperature  and  the  presence  of  severe  central  nervous  system  dysfunction.Classic  (nonexertional)  heat  stroke  affects  the  elderly  and  the  chronically  ill  and  is  associated  with  high  morbidity  and  mortality  rates.Exertional  heat  stroke  affects  younger  individuals  who  exercise  in  hot  environments,  and  it  develops  over  a  short  period.Immediate  conductive  or  evaporative  cooling  should  be  instituted  for  heat  stroke  victims  with  a  core  temperature  above  41°C.Malignant  hyperthermia  is  a  rare  syndrome  of  hyperthermia,  muscle  contractions,  and  cardiovascular  instability  triggered  by  succinyl  choline  and  inhaled  anesthetics.Management  of  malignant  hyperthermia  includes  the  prompt  recognition  of  the  syndrome,  discontinuation  of  the  inciting  drug,  administration  of  dantrolene,  and  supportive  care.Neuroleptic  malignant  syndrome  is  an  idiosyncratic  reaction  to  neuroleptic  drugs  characterized  by  hyperthermia,  muscle  rigidity,  alterations  in  mental  status,  autonomic  dysfunction,  and  rhabdomyolysis.Treatment  of  neuroleptic  malignant  syndrome  includes  discontinuation  of  the  triggering  drug,  administration  of  dantrolene  for  muscle  rigidity  and  hyperthermia,  administration  of  dopaminergic  drugs  such  as  bromocriptine  and  amantadine,  and  supportive  care.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2023/11/28
UR  - accessanesthesiology.mhmedical.com/content.aspx?aid=2282701
ER  -