TY - CHAP M1 - Book, Section TI - Chapter 71. Diagnosis & Management of Intraspinal, Epidural, & Peripheral Nerve Hematoma A1 - Jabri, Rasha S. A1 - Deschner, Steven A1 - Benzon, Honorio T. A2 - Hadzic, Admir Y1 - 2007 N1 - T2 - NYSORA Textbook of Regional Anesthesia and Acute Pain Management AB - Spinal epidural hematoma (SEH) is an accumulation of blood in the potential space between the dura and the bone. Hemorrhage into the spinal canal most commonly occurs in the epidural space because of the prominent epidural venous plexus. SEH may be spontaneous or may follow minor trauma, such as lumbar puncture or neuraxial anesthesia. It is more likely to occur in anticoagulated or thrombocytopenic patients, or in those with liver disease or alcoholism. Approximately one quarter to one third of all cases are associated with anticoagulation therapy.1,2 Spontaneous bleeding is rare but may be seen with anticoagulation, thrombolysis, blood dyscrasias, coagulopathies, thrombocytopenia, neoplasms, vascular malformations, or vertebral hemagioma.3,4 The peridural venous plexus is usually involved, though arterial sources of hemorrhage also occur.5 SEHs are mostly venous in nature because the venous plexus lacks valves, and the plexus has been shown to permit a reversal in blood flow during pressure increase from physical activity.6 Hematoma sites are usually found in the cervical and thoracic spine.7 Most SEHs are located dorsal to the dural sac because of the firm adherence of the dural sac to the posterior longitudinal ligament in the ventral aspect of the spinal canal. The dorsal aspect of the thoracic or lumbar region is involved commonly, and expansion is limited to a few vertebral levels. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/16 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=3508962 ER -