TY - CHAP M1 - Book, Section TI - Acute Liver Failure A1 - Kandiah, Prem A. A1 - Nanchal, Rahul A1 - Subramanian, Ram M. A2 - Schmidt, Gregory A. A2 - Kress, John P. A2 - Douglas, Ivor S. Y1 - 2023 N1 - T2 - Hall, Schmidt and Wood’s Principles of Critical Care, 5th Edition AB - KEY POINTSAcute liver failure is a syndrome with sudden loss of liver function characterized by transaminitis, coagulopathy, and encephalopathy in a patient without previous liver disease.Etiologies vary greatly; however, acetaminophen toxicity and viral hepatitis infections are among the most common.Shock, kidney failure, encephalopathy, and sepsis are common complications of acute liver failure.High-volume plasma exchange and continuous renal replacement therapy are interventions that are associated with improved survival.Aggressive supportive care at a center that performs liver transplantation optimizes patient outcomes. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/11/06 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1201809862 ER -